PRODUCT STABILITY PRODUCT STABILITY What Is Product Instability? “The incapacity or incapability of a particular formulation in a specific container to remain within a particular chemical, microbiological, therapeutical, physical & toxicological specification.” What Is Product Stability? “The capacity or the capability of a particular formulation in a specific container to remain with in particular chemical, microbiological, therapeutical, physical & toxicological specification.” FACTORS EFFECTING PRODUCT STABILITY: Factors effecting the product stability are as under 1. PH 2. Temperature 3. Moisture 4. Light 5. Radiations TYPES OF PRODUCT INSTABILITY: Product stability can be divided into two major types 1. Physical degradation 2. Chemical degradation PHYSICAL DEGRADATION: Definition: “Degradation, which results into the change of physical nature of the product.” Types: Types of physical degradation are as under 1. Loss of volatile components 2. Loss of H2O 3. Absorption of H2