DIURETICS DOWNLOAD [PDF] DOWNLOAD [PPT] Kidneys: • Represent 0.5% of total body weight,but receive ~25% of the total arterialblood pumped by the heart . Each contains from one to two million nephrons NEPHRON: Blood processing unit which serves to produce urine , 1 million per kidney . IT Consists of ¨ – The glomerulus , The proximal convoluted tubule , The loop of Henle , The distal convoluted tubule Functions of Urinary System ¨ Kidneys carry out four functions ¤ Filter nitrogenous wastes, toxins, ions, etc. from blood to be excreted as urine. (Excretion of Wastes) ¤ Regulate volume and chemical composition of blood (water, salts, acids, bases ). (Fluid and electrolytes ) ¤ Produce regulatory enzymes. (Enzyme Production) n Renin – regulates BP/ kidney function n Erthropoeitin – stimulates RBC production from marrow. ¤ Metabolism of Vitamin D to active form . (Metabolism) Diuretics: • Increase output of urine . Primary indication...